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sarms bodybuilding supplements
What is S4?
As a research chemical, Andarine S-4 belongs to a class of chemicals known as SARMs or selective androgen receptor modulators.
As an orally active partial agonist for androgen receptors, S-4 is effective in not only maintaining lean body mass (LBM) but actually increasing it.
S4 was designed for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the non-steroidal androgen antagonist bicalutamide as a lead compound. Compared to testosterone and other anabolic steroids and pro hormones, the advantage of SARMs such as S-4 is that they do not have androgenic activity in non-skeletal-muscle tissues. Like typical androgens, SARMs still bind to the androgen receptor however SARMs create selective anabolic activity at certain androgen receptors and not others, hence their name.
What is the Half-Life of S4?
Because of this, it’s common for users to split the dosage so its effect can be continuous all throughout the day.
When compared to other SARMs, S4 is known to have a short-acting cycle. Specifically, S4’s half life is between 4 to 6 hours.
Advantages Of S4 when compared to Steroids/Prohormones
There is no need for on cycle supports such as milk thistle for the liver, policosanol or RYR for cholesterol etc.
There is no need for pre cycle supports such as Hawthorn berry.
High oral biovailabilty without significant damage to your liver like with oral steroids/pro hormones
Great sense of well being while on, (without the agression which can often detrimentally impact users daily lifes).
Some supression may be present at doses of 50mg+ run for longer than 4 weeks, however a stringent PCT of prescription SERMs like Nolva or Clomid is not necessary.
No need for a long time period off between cycles; the recomended time of period for a normal cycle would be Time on + PCT, so for a typical 6 week cycle and 4 week PCT, a user would have to wait another 10 weeks after PCT to start another cycle.
What Other SARMs Stack Well with S4
Andarine is effective enough to be used as a standalone.
However, it’s still possible to stack it with other SARMs to increase its effectiveness.
It’s in the process of cutting in which most people would stack S4 with GW-501516 and Ostarine.
How Long Until You See Results
S4 is a relatively fast-acting SARM. Furthermore, there are also other factors that may impact the results, like diet and physical activity program. In fact, you should be able to notice the first results in just 7 days. Of course, the exact time frame is hard to determine as each body has its own physiology.
How does S4 work?
Being a SARM, S4 binds to the androgen receptor while demonstrating bone and muscular anabolic activity. This is how S4 is capable of building muscle. By binding to and activating the androgen receptor, S4 alters the expression of genes while increasing protein synthesis.
SARMS represent numerous various qualities and choices of use for a variety of goals and conditions. SARMS were designed and intended to deal with muscle wasting conditions such as cancer, osteoperosis, AIDS and age-related issues.
S-4 has the unique capability to bind to the androgen receptor in muscle and bone at the rate of 1/3 the affinity of testosterone.
S4 has the ability to provide muscle development much like steroids.
The vital distinction is that unlike other steroids, SARMS are non-steroidal and do not produce the development result steroids cause on the prostate and other sexual organs. Another crucial use of SARMS is for bodybuilding. SARMS have actually become prevalently used throughout the bodybuilding world for efficiency improvement and as a far more secure alternative to steroid use.
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