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|Product Name:||Anastrozole||Other Name:||Arimidex|
|Function:||Anti Breast Cancer||Resend Policy:||Available|
Anastrozole Anti Estrogen Steroids for Breast Cancer Arimidex Powder Cas 53-41-8
Anastrozole is a powerful Aromatase Inhibitor, it is an off-white powder with a molecular weight of 293.4. Anastrozole has moderate aqueous solubility (0.5 mg/mL at 25°C); solubility is independent of pH in the physiological range. Anastrozole is freely soluble in methanol, acetone, ethanol, and tetrahydrofuran, and very soluble in acetonitrile.
Anastrozole has been one of the leading anti-estrogenic medications on the market. The compound has proven far more effective in breast cancer treatment plans than Tamoxifen Citrate (Nolvadex), although both compounds are regularly used.
Anastrozole is an aromatase inhibitor, an anti-cancer medication use for the adjuvant or initial treatment of breast cancer in post-menopausal women. Estrogen causes or increases growth of certain breast cancers. Anastrozole works by blocking aromatase enzyme, which is involved in estrogen production in the body. This leads to decreased tumor size or delayed progression of tumor growth in some women.
Anastrozole is used to treat breast cancer in women after menopause. Some breast cancers are made to grow faster by a natural hormone called estrogen. Anastrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.
Anastrozole will actively inhibit the aromatase enzyme, thereby preventing the testosterone to estrogen conversion and any related affects that could come with elevated estrogen levels. Elevated estrogen levels can lead to gynecomastia and excess water retention most commonly, which can in turn promote high blood pressure if water retention becomes severe. The use of Anastrozole when needed will prevent such related actions baring any secondary or unrelated issues. The compound is so effective data has shown it has the ability to suppress estrogen by as much as 80%.
Anastrozole also carries traits outside estrogen suppression, primarily natural testosterone stimulation. This AI has the ability to stimulate the release of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), two hormones that signal the testicles to produce more testosterone when released.
How anastrozole works?
Anastozole lowers the amount of oestrogen in the body. The female sex hormones oestrogen and progesterone stimulate many breast cancers to grow. Lowering the level of oestrogen can stop or slow the growth of breast cancer cells.
Anastrozole blocks a process called aromatisation that changes sex hormones called androgens into oestrogen. This happens mainly in the fatty tissues, muscle and the skin and needs a particular enzyme called aromatase.
A, Adjuvant Treatment
ARIMIDEX is indicated for adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer.
B, First-Line Treatment
ARIMIDEX is indicated for the first-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer.
C, Second-Line Treatment
ARIMIDEX is indicated for the treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy. Patients with ER-negative disease and patients who did not respond to previous tamoxifen therapy rarely responded to ARIMIDEX.
The dose of ARIMIDEX is one 1 mg tablet taken once a day. For patients with advanced breast cancer, ARIMIDEX should be continued until tumor progression. ARIMIDEX can be taken with or without food.
For adjuvant treatment of early breast cancer in postmenopausal women, the optimal duration of therapy is unknown. In the ATAC trial, ARIMIDEX was administered for five years.
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Store at controlled room temperature, 20-25°C (68-77°F).