Shanghai Stero R&D Co,. Ltd

testosterone, nandrolone, trenbolone, equipoise, masteron, primobolan, antiestrogen, growth hormone, injection vials, water based suspension, hgh, sarms, prohormones

Home
Products
About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
Home ProductsEstrogen Steroid Hormone

Mild Estrogen Steroid Hormone Estrone Increased Body Weight Cas 53-16-7

Good quality Professional Bodybuilding Steroids for sales
Good quality Professional Bodybuilding Steroids for sales
Everything is great and very high quality. I will be in touch with you soon for futher services, Really appreciate your fast shipping and good quality

—— Mr.Carlos

Yes I did it, arrived yesterday, and I tried it today for the first time with great results. Thank you.

—— Mr.Benjamin

Just letting you know I received the package today, and thanks for the excellent services, Will be ordering again very soon.

—— Mr.Sergey

Yes I have had no issue with quality of products you provided me with , also all my customers are also happy with quality thank you very much.

—— Mr.Drake

Thanks for stuff, ran a test on myself last night... very happy with quality and would like to order a repeat order, thank you.

—— Mr.Hannon

I'm Online Chat Now

Mild Estrogen Steroid Hormone Estrone Increased Body Weight Cas 53-16-7

China Mild Estrogen Steroid Hormone Estrone Increased Body Weight Cas 53-16-7 supplier

Large Image :  Mild Estrogen Steroid Hormone Estrone Increased Body Weight Cas 53-16-7

Product Details:

Place of Origin: China
Brand Name: Shanghai Stero
Certification: SGS, ISO9001, GMP
Model Number: Cas 53-16-7

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Factory Wholesale Price
Packaging Details: Professional Discreet Package, Special Channel
Delivery Time: Within 4hours After Payment Confirmed
Payment Terms: Western Union, MoneyGram, Bank transfer
Supply Ability: 3000 kg / month
Detailed Product Description
Product Name: Estrone Standard: Enterprise Standard
Appearance: White Powder Purity: 98% Min
Function: Increased Body Weight, Bodybuilding Resend Policy: Available

Mild Estrogen Steroid Hormone Estrone Increased Body Weight Cas 53-16-7

 

 

What is Estrone?

Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol. Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver. Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women. The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.

 

Estrone is an estrogenic hormone secreted by the ovary as well as adipose tissue It is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy.

 

 

Chemical Info

Chemical Name: 3-hydroxy-estra-1,3,5(10)-trien-17-one
CAS Number: 53-16-7
Molecular Formula: C18H22O2
EINECS 200-164-5
Formula Weight: 270.4
Melting Point 258-261℃
Purity: ≥95%
Appearence: Crystalline solid
Storage: -20°C
Stability: ≥ 2 years
TECHNICAL SUPPORT Contact: Deca Lee WhatsApp: +8617068712531

 

 

Effects

There is growing concern about the biologic effects of steroid hormones in impacted waterways. There is increasing evidence of enhanced transport and biological effects stemming from steroid hormones associated with soils or sediments;

 

however, there are limited studies evaluating how steroid hormone distribution between various particle sizes within whole sediments affects steroid fate. In this study, sorption of 17β-estradiol, Estrone, progesterone, and testosterone was evaluated to different size fractions of two natural sediments, a silty loam and a sandy sediment, to determine the steroid sorption capacity to each fraction and distribution within the whole sediment.

 

Sorption isotherms for all steroid hormones fit linear sorption models. Sorption capacity was influenced more by organic carbon content than particle size. Interactions between size fractions were found to affect the distribution of steroids within the whole sediments.

 

All four steroids preferentially sorbed to the clay and colloids in the silty loam sediment at the lowest aqueous concentration (1ng/L) and as aqueous concentration increased, the distribution of sorbed steroid was similar to the distribution by weight of each size fraction within the whole sediment. In the sandy sediment, preferential sorption to fine particles was observed.

 

Breast cancer resistance protein (BCRP), an adenosine triphosphate-binding cassette transporter, confers resistance to a series of anticancer reagents, including mitoxantrone, SN-38 and topotecan. In the present study, we found that Estrone and 17beta-estradiol potentiated the cytotoxicity of mitoxantrone, SN-38 and topotecan in BCRP-transduced K562 cells (K562 / BCRP). These estrogens showed only a marginal effect, or none, in parental K562 cells. Estrone and 17beta-estradiol increased the cellular accumulation of topotecan in K562 / BCRP cells, but not in K562 cells, suggesting that these estrogens inhibit the BCRP-mediated drug efflux and overcome drug resistance.

 

Estrone is a relatively abundant hormone widely distributed in tissues of animal and plant origin. It is a mild estrogen that induces increases in body weight in experimental animals. The relative abundance of Estrone esters in animal tissues suggests that it may also be found in foods, from which it may alter the mechanisms of body weight control.

 

 

Aim of Study

To measure the total Estrone content in food and to determine whether this may affect body weight. The content of Estrone was zero in some vegetables, but significant in fruits, meats, and especially fats, both of plant and animal origin. The application of these analyses to a standard recommended diet for humans may result in intakes of more than 1 mumol of Estrone per day, a figure comparable to the estrogen production by women.

 

When rats were exposed to a raised Estrone content in a fat-rich diet, they significantly increased their body weights, doubling their rate of growth (1.99 g/day) compared with controls (0.81 g/day), but maintaining their plasma composition and the proportions of lipid, water, and protein in their carcasses.

 

 

Conclusion

The widely distributed Estrone esters in food and their relatively high concentrations may result in high free hormone intakes in humans. The continued and massive intake of Estrone may enhance tissue deposition and lead to obesity.

 

 

Mild Estrogen Steroid Hormone Estrone Increased Body Weight Cas 53-16-7

Contact Details
Shanghai Stero R&D Co,. Ltd

Contact Person: Deca Lee

Send your inquiry directly to us (0 / 3000)