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|Effects:||Breast Cancer||Half Life:||Short|
What is Letrozole
Letrozole reduces estrogen levels in postmenopausal women, which can slow the growth of certain types of breast tumors that need estrogen for growth in the body.
Letrozole is used to treat breast cancer in postmenopausal women. This is often given to women who took tamoxifen (Nolvadex, Soltamox) for 5 years.
For pre-contest bodybuilders, Letrozole is almost a necessity to eliminate water retention and achieve the ripped look necessary to compete in today’s bodybuilding world. it is only necessary to be used for the last 4-6 weeks, to eliminate excess estrogen and water retention. After using Letrozole I recommend staying away from any estrogen suppression for at least a month to try to normalize the body.
Letrozole Functions & Traits:
Letrozole is an AI, which holds the purpose of blocking the aromatase enzyme, which is in turn responsible for the production of estrogen.
However, Letrozole can be useful in such a plan in conjunction with exogenous testosterone in order to combat possible side effects.
Letrozole also carries the ability to increase natural testosterone production through an increase in Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH).Without question, when it comes to low testosterone treatment exogenous testosterone is generally the only thing that makes sense. We will look into this in the effects section. There have been physicians who have chosen Letro as it’s often known to treat low testosterone conditions, but this is normally not the preferred method of treatment.
By inhibiting estrogen production, this lowers total serum estrogen levels in the body. This will be useful to the breast cancer patient on the basis of such cancer often feeding off the estrogen hormone.
Effects of Letrozole:
Letrozole as an anti-estrogen is extremely beneficial to breast cancer patients. Many forms of breast cancer actively feed off the estrogen hormone.
Nolvadex actively binds to the estrogen receptor, thereby preventing estrogen from binding. However, it does not inhibit or lower production. For years Nolvadex was the preferred form of treatment for this purpose. Nolvadex is still extremely valuable in breast cancer treatment plans, but many physicians, especially in extreme cases have begun to use AI’s first.
By inhibiting the production of estrogen, which in turn lowers the amount of circulating estrogen in the body, this has the ability to starve the cancer.
For the anabolic steroid user, the same anti-estrogenic effect provided by Letrozole is tremendously beneficial. If water retention becomes severe, this can in turn promote high blood pressure. While many anabolic steroids have the ability to aromatize and promote an increase in estrogen, not all anabolic steroids carry this ability. Many anabolic steroids have the ability to increase estrogen levels due to testosterone’s interaction with the aromatase enzyme. As estrogen levels rise, this can lead to gynecomastia and excess water retention.
However, many common steroids carry this ability including Methandrostenolone (Dianabol) as well as all forms of testosterone.
The Nandrolone (Deca Durabolin, Durabolin, NPP, etc.) and Boldenone (Equipoise) hormone also carry the ability to aromatize to a degree. Progesterone has the ability to stimulate the estrogenic mechanism and can lead to gynecomastia. Nandrolone will aromatize at approximately 20% the rate of testosterone and Boldenone at approximately 50%.
The probability is increased with Nandrolone as it carries a strong progestin nature. AI’s like Letrozole can be useful when using all the aforementioned steroids.
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